Yue Dai Selected Research

norisoboldine

4/2024	Corrigendum to "Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues" [Toxicology and Applied Pharmacology, 282/1 (2015) 90-99].
1/2023	Discovery of Norisoboldine Analogue III11 as a Novel and Potent Aryl Hydrocarbon Receptor Agonist for the Treatment of Ulcerative Colitis.
1/2022	Norisoboldine induces the development of Treg cells by promoting fatty acid oxidation-mediated H3K27 acetylation of Foxp3.
12/2021	NMR-based untargeted metabolomics approach to investigate the systemic lipid metabolism regulation of norisoboldine in collagen-induced arthritis rats.
1/2019	Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex.
3/2018	Norisoboldine, a natural aryl hydrocarbon receptor agonist, alleviates TNBS-induced colitis in mice, by inhibiting the activation of NLRP3 inflammasome.
1/2018	Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway.
1/2017	The absorption enhancement of norisoboldine in the duodenum of adjuvant-induced arthritis rats involves the impairment of P-glycoprotein.
1/2016	Norisoboldine, an isoquinoline alkaloid, acts as an aryl hydrocarbon receptor ligand to induce intestinal Treg cells and thereby attenuate arthritis.
12/2015	Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons.

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Yue Dai Research Topics

Disease

33	Arthritis (Polyarthritis) 02/2024 - 05/2007
29	Experimental Arthritis 04/2024 - 04/2009
26	Colitis 01/2024 - 12/2014
25	Neoplasms (Cancer) 01/2024 - 04/2008
24	Inflammation (Inflammations) 09/2023 - 09/2002
23	Rheumatoid Arthritis 02/2024 - 05/2007
9	Hypertension (High Blood Pressure) 04/2024 - 07/2010
9	Fibrosis (Cirrhosis) 01/2023 - 06/2013
9	Body Weight (Weight, Body) 03/2015 - 05/2007
8	Pulmonary Fibrosis (Fibrosing Alveolitis) 11/2022 - 10/2013
7	Ulcerative Colitis 01/2024 - 12/2015
7	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2022 - 08/2015
7	Hypersensitivity (Allergy) 01/2018 - 03/2004
6	Infections 01/2021 - 12/2014
5	Obesity 03/2024 - 08/2010
5	Hypoxia (Hypoxemia) 03/2023 - 04/2016
4	Atherosclerosis 03/2024 - 01/2021
4	Cardiovascular Diseases (Cardiovascular Disease) 09/2023 - 09/2018
4	Ureteral Obstruction 01/2023 - 06/2013
4	Wounds and Injuries (Trauma) 10/2022 - 06/2008
4	Keloid 08/2017 - 08/2012
4	Cicatrix (Scar) 11/2013 - 11/2008
4	Sepsis (Septicemia) 07/2012 - 02/2009
3	Abdominal Obesity 03/2024 - 01/2013
3	Neoplasm Metastasis (Metastasis) 01/2023 - 04/2016
3	Colitis-Associated Neoplasms 10/2022 - 10/2020
3	Asthma (Bronchial Asthma) 04/2022 - 01/2012
3	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2017
3	Stroke (Strokes) 01/2021 - 03/2019
3	Weight Gain 01/2018 - 08/2010
3	Hepatocellular Carcinoma (Hepatoma) 07/2015 - 11/2011
3	Edema (Dropsy) 10/2013 - 09/2002
3	Overweight 03/2013 - 08/2010
3	Anaphylaxis (Anaphylactic Shock) 01/2005 - 09/2002
2	Malaria 05/2024 - 09/2023
2	Dyslipidemias (Dyslipidemia) 03/2024 - 01/2022
2	Type 2 Diabetes Mellitus (MODY) 03/2024 - 09/2015
2	Pathologic Constriction (Stenosis) 03/2024 - 01/2021

Drug/Important Bio-Agent (IBA)

16	norisoboldineIBA 04/2024 - 08/2012
15	Dextran SulfateIBA 10/2023 - 12/2014
13	AlkaloidsIBA 01/2022 - 05/2007
11	madecassosideIBA 12/2020 - 06/2008
10	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 07/2023 - 01/2015
9	Proteins (Proteins, Gene)FDA Link 05/2024 - 06/2009
9	TriterpenesIBA 12/2023 - 06/2008
9	CollagenIBA 10/2019 - 05/2007
8	arctigeninIBA 01/2024 - 12/2014
8	CytokinesIBA 01/2024 - 04/2008
8	Interleukin-6 (Interleukin 6)IBA 01/2021 - 08/2012
8	SaponinsIBA 03/2015 - 05/2006
7	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 10/2020
7	Therapeutic UsesIBA 01/2023 - 04/2010
7	tetrandrineIBA 01/2022 - 11/2015
6	Interleukin-17 (Interleukin 17)IBA 04/2022 - 05/2015
6	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 10/2013
6	AntigensIBA 01/2021 - 07/2003
5	Messenger RNA (mRNA)IBA 03/2024 - 06/2009
5	LipopolysaccharidesIBA 02/2024 - 10/2011
5	morinIBA 01/2023 - 12/2015
5	InflammasomesIBA 01/2023 - 01/2018
5	sinomenineIBA 10/2022 - 05/2015
5	madecassic acidIBA 01/2022 - 12/2014
5	isoquinolineIBA 12/2021 - 03/2013
5	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amideIBA 01/2021 - 01/2018
5	ScopoletinIBA 07/2015 - 08/2010
4	bergeninIBA 05/2024 - 01/2017
4	FlavonoidsIBA 12/2022 - 01/2005
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2022 - 01/2013
4	Antihypertensive Agents (Antihypertensives)IBA 01/2020 - 03/2014
4	Interleukin-10 (Interleukin 10)IBA 01/2017 - 03/2015
4	peoniflorinIBA 06/2016 - 10/2011
4	coumarinIBA 12/2013 - 07/2009
4	Histamine (Histamine Dihydrochloride)FDA Link 05/2013 - 09/2002
4	Sodium Glutamate (Accent)IBA 03/2013 - 08/2010
4	p-Methoxy-N-methylphenethylamineIBA 01/2005 - 09/2002
3	Dextrans (Dextran)FDA Link 01/2024 - 01/2021
3	Mechanistic Target of Rapamycin Complex 1IBA 08/2023 - 08/2015
3	LigandsIBA 12/2022 - 01/2016
3	Triglycerides (Triacylglycerol)IBA 11/2022 - 12/2014
3	GlycosidesIBA 11/2022 - 02/2011
3	Butyrates (Butyrate)IBA 11/2022 - 11/2019
3	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2022 - 04/2016
3	EnzymesIBA 04/2022 - 01/2022
3	CurcuminIBA 03/2021 - 05/2015
3	Uric Acid (Urate)IBA 01/2021 - 08/2010
3	LipidsIBA 01/2021 - 12/2014
3	Leucine (L-Leucine)FDA Link 01/2020 - 08/2015
3	BerberineIBA 11/2019 - 01/2017
3	Peroxidase (Myeloperoxidase)IBA 01/2018 - 10/2009
3	Collagen Type II (Type II Collagen)IBA 12/2015 - 05/2007
3	Phosphotransferases (Kinase)IBA 01/2015 - 08/2012
2	artemisinin (artemisinine)IBA 05/2024 - 09/2023
2	Apolipoproteins E (ApoE)IBA 03/2024 - 07/2021
2	IronIBA 02/2024 - 07/2008

Therapy/Procedure

17	Oral Administration 11/2023 - 06/2008
15	Therapeutics 05/2024 - 08/2012
10	Chinese Traditional Medicine (Traditional Chinese Medicine) 02/2024 - 07/2009
3	Intraperitoneal Injections 07/2022 - 01/2011
3	Ligation 02/2011 - 02/2009
3	Punctures 02/2011 - 02/2009